Cyfuse
Develops and sells the Regenova bio 3D printer system, which fabricates three-dimensional tissues and organs using a scaffold-free, needle-array-based 'Kenzan Method' for regenerative medicine applications.
- CEO / Founder
- Shizuka Akieda
- Team Size
- 11-50
- Stage
- Public
- Total Funding
- $24.5M
- Latest Round
- IPO
- Key Investors
- JAFCO Group
Technology & Products
Key Products
Regenova Bio 3D Printer; Human 3D Mini-Liver models for drug testing
Technological Advantage
The scaffold-free approach is a key differentiator, potentially leading to more biologically functional tissues. The technology is protected by patents (e.g., US11339361B2, WO2017131241A1) and has been developed in collaboration with industrial partners like Shibuya Kogyo for robotic control. Its transition into clinical trials (e.g., knee bone-cartilage repair) validates its path to regulated medical applications.
Differentiation
Value Proposition
Enables the creation of complex, scaffold-free 3D cellular structures (like nerve conduits, blood vessels, and bone-cartilage interfaces) with high cell viability, accelerating regenerative medicine R&D and clinical translation.
How They Differentiate
Cyfuse's scaffold-free Kenzan Method contrasts with most competitors' extrusion-based or light-based bioprinting that often requires hydrogel scaffolds. This aims to produce more natural tissue structures and better cell-cell interactions.
Market & Competition
Target Customers
Research institutions, pharmaceutical companies, and regenerative medicine developers
Industry Verticals
Regenerative Medicine; Pharmaceutical Research; Medical Research
Competitors
Organovo; Aspect Biosystems; Allevi (3D Systems)
Growth & Milestones
Growth Metrics
Listed on the Tokyo Stock Exchange Growth Market in 2022; developing a new bio 3D printer with NSK for commercial production of 3D cell products.
Major Milestones
Founded (2010); Series A ~$4.8M (2013); Listed on Tokyo Stock Exchange Growth Market (2022); Initiated physician-led clinical trial for knee bone-cartilage repair (2024); Partnership with PHC for production tech (2025)
Notable Customers
NSK Ltd.; PHC Holdings Corporation