Trestle Biotherapeutics

PlatformSan Diego, USAFounded 2020

A preclinical-stage biotechnology company developing implantable, bioengineered kidney tissues to eliminate the need for dialysis and traditional organ transplants.

CEO / Founder
Ben Shepherd
Team Size
11-50
Stage
Preclinical; currently engaged in IND-enabling research and a 2025 strategic collaboration with Humacyte to develop vascularized organ prototypes.
Total Funding
$1,200,000+
Latest Round
Wellcome Leap HOPE Program Award (Mar 2024)
Key Investors
["Y Combinator","Acequia Capital","Black Mountain Ventures","KidneyX","Wellcome Leap"]

Technology & Products

Key Products

["Bioengineered Implantable Kidney Tissue","Vascularized Kidney Organoids","Stem cell-derived Ureteric Bud and Nephron Progenitor Platform","3D Biofabricated Renal Tissue Models"]

Technological Advantage

Holds exclusive licenses to foundational bioprinting and stem cell technologies from Harvard's Wyss Institute and Kumamoto University, enabling the production of complex renal structures at commercial scale.

Market & Competition

Target Customers

Patients with end-stage renal disease (ESRD), nephrology clinics, healthcare systems, and organ transplant centers.

Industry Verticals

["Biotechnology","Regenerative Medicine","Nephrology","Healthcare"]

Competitors

["eGenesis","Miromatrix Medical (United Therapeutics)","IVIVA Medical","Organovo"]