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Prellis Biologics

ApplicationBerkeley, United StatesFounded 2016· One of 313 Application companies tracked by AMPulse

Develops holographic bioprinting technology for creating complex human tissues and lymph node models to enable rapid antibody discovery, reducing lead times from 9 months to 16 days.

CEO / Founder
Michael Nohaile
Team Size
11-50
Stage
Active
Total Funding
$64.5M
Latest Round
Series C
Key Investors
Avidity Partners, Celesta Capital, Khosla Ventures, True Ventures, Indie Bio (SOSV)

Technology & Products

Key Products

Externalized Immune System (EXIS) platform; Lymph node organoids (LNOs)

Technological Advantage

CLAIMED: Proprietary laser-based holography enables large, complex tissue co-cultures. VERIFIED: Platform demonstrated discovery of 300 SARS-CoV-2 antibodies in 16 days, significantly faster than the 9-month industry standard.

Differentiation

Value Proposition

Reduces antibody discovery cost and time (9 months to 16 days) by utilizing an Externalized Immune System (EXIS) platform that mimics human immune responses without animal testing.

How They Differentiate

Differentiates through high-resolution (10-20 micron) holographic printing vs. traditional bioprinting, specifically optimized for immune system modeling and antibody discovery rather than structural tissue replacement.

Market & Competition

Target Customers

Biotechnology and pharmaceutical industries

Industry Verticals

Biotechnology; Pharmaceuticals

Competitors

Aspect Biosystems (microfluidic bioprinting for therapeutic tissues), Cellink (BICO) (light-based and extrusion bioprinting systems), Organovo (3D bioprinted human tissues for drug discovery and development).

Growth & Milestones

Growth Metrics

Antibody discovery time reduced from 9 months to 16 days; Generated 300 human antibodies binding SARS-CoV-2.

Major Milestones

Founded in October 2016; Generated 300 human antibodies for SARS-CoV-2; Raised $35M Series C funding; Appointed Mike Nohaile as CEO

Notable Customers

Bristol Myers Squibb, Eli Lilly and Company