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R3 Bio

ApplicationSan Francisco, California, USAFounded 2021· One of 381 Application companies tracked by AMPulse

A biotechnology startup developing cell-based research platforms using cellular reprogramming and stem-cell-derived systems to create New Approach Methodologies (NAMs) that reduce reliance on animal testing.

CEO / Founder
John Schloendorn
Team Size
1-10
Stage
Active
Total Funding
$1.0M
Latest Round
Seed
Key Investors
Tim Draper, Immortal Dragons, LongGame Ventures

Technology & Products

Key Products

Cell-based research platforms, stem-cell-derived model systems, New Approach Methodologies (NAMs) for preclinical research, computational analysis platforms.

Technological Advantage

Utilizes advanced CRISPR gene editing to 'knock out' brain development genes in stem cells, allowing for the growth of integrated organ systems in situ rather than isolated lab-grown organoids, which lack the systemic complexity required for accurate drug testing.

Differentiation

Value Proposition

Provides cell-based research platforms and New Approach Methodologies (NAMs) that reduce reliance on animal testing through stem-cell-derived systems and advanced analytical methods.

How They Differentiate

R3 Bio combines cellular reprogramming, stem-cell-derived systems, and computational analysis to build integrated biological signaling models that capture cross-cellular signals often lost in simpler assays, aligned with regulatory modernization efforts.

Market & Competition

Target Customers

Pharmaceutical companies, medical research institutions, contract research organizations (CROs), and eventually transplant hospitals.

Industry Verticals

["Biotechnology","Pharmaceuticals","Healthcare","Regenerative Medicine","Longevity & Life Extension"]

Competitors

Renewal Bio, eGenesis, Revalia Bio

Growth & Milestones

Growth Metrics

Transitioned from multi-year stealth mode to public R&D phase in March 2024; team size estimated at 1-10 employees.

Major Milestones

["Founded in 2021 by Alice Gilman and John Schloendorn.","Secured initial Seed funding from billionaire investor Tim Draper and Immortal Dragons in early 2024.","Emerged from stealth mode in March 2024 with major features in Wired and MIT Technology Review.","Updated company location to San Francisco (with upcoming second location in Puerto Rico) per website FAQ."]

Notable Customers

N/A (Currently in R&D/Pre-revenue stage)