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Advanced BioMatrix

MaterialsCarlsbad, California, USAFounded 2008· One of 955 Materials companies tracked by AMPulse

Develops high-purity bio-inks and extracellular matrix materials for 3D bioprinting and tissue engineering applications, enabling reproducible cell culture and research.

CEO / Founder
Mike Beames
Team Size
1-10
Stage
Acquired
Total Funding
$15M
Latest Round
Acquired
Key Investors
BICO Group

Technology & Products

Key Products

Collagen bio-inks (e.g., PureCol®); Recombinant laminin proteins (Laminin-511, Laminin-411, Laminin-221); Extracellular matrix proteins; Adhesion peptides/proteins; Chemically modified proteins and polysaccharides

Technological Advantage

Proprietary purification and formulation processes yield bio-inks with exceptional purity and functionality, critical for reproducible 3D tissue models; integrated into BICO's bioprinting ecosystem creating switching costs.

Differentiation

Value Proposition

Provides standardized, high-purity bio-inks and reagents that reduce variability in 3D cell culture and bioprinting experiments, accelerating research timelines and improving reproducibility for life-saving therapies.

How They Differentiate

Focuses exclusively on high-purity bio-inks and ECM materials for 3D bioprinting, whereas competitors like Mission Bio target single-cell genomics; offers the highest density collagen ink on the market with standardized consistency.

Market & Competition

Target Customers

Research institutions, pharmaceutical companies, biotech labs, and academic researchers in tissue engineering and drug discovery.

Industry Verticals

Biotechnology; Pharmaceuticals; Academic Research; Medical Research

Competitors

DiaCarta; Mission Bio; Quadrants Scientific

Growth & Milestones

Growth Metrics

Advanced BioMatrix obtained approximately USD 3 million revenue with adjusted EBITDA margin of around 50% in latest fiscal year prior to 2021 acquisition[3]. Acquired by BICO for USD 15 million cash and debt-free, plus potential USD 3 million earn-out[2][3][9].

Major Milestones

Acquired by BICO Group in August 2021 for $15M cash plus up to $3M earn-out; Integrated into BICO's Life Science Solutions division (formerly Bioprinting)

Notable Customers

Sells to research institutions, pharmaceutical and biotech companies[2][3]. No specific notable customers named.

https://www.advancedbiomatrix.com

Why this company matters

Advanced BioMatrix develops high-purity bio-inks and extracellular matrix materials for 3D bioprinting and tissue engineering. Acquired by BICO Group in 2021 for $15 million, the company fills a gap in the bioprinting workflow: reproducible, standardized materials that reduce experimental variability. Its products are used by research institutions, pharmaceutical companies, and biotech labs focused on drug discovery and regenerative medicine.

The company's core offering includes collagen bio-inks such as PureCol, recombinant laminin proteins (Laminin-511, Laminin-411, Laminin-221), and chemically modified proteins and polysaccharides. These materials are formulated for material extrusion bioprinting (MEX) and are designed to support consistent cell viability and tissue model formation. Advanced BioMatrix claims over 25 years of R&D in kinetic gel testing, gel stiffness rheometry, and protein purification, which underpins its reputation for purity and batch-to-batch consistency.

As part of BICO's Life Science Solutions division, Advanced BioMatrix benefits from integration with BICO's bioprinting hardware and lab automation portfolio, creating potential switching costs for users. The company's focus on high-purity ECM materials differentiates it from competitors such as Mission Bio, which targets single-cell genomics. A key open question is how the company will scale production to meet growing demand from pharmaceutical R&D while maintaining its quality standards.

Advanced BioMatrix reported approximately $3 million in revenue with an adjusted EBITDA margin of around 50% in its last fiscal year before acquisition. The company employs fewer than 10 people and operates out of Carlsbad, California.