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Colossal Biosciences

ApplicationDallas, United StatesFounded 2021· One of 686 Application companies tracked by AMPulse

Dallas-based biotechnology and genetic engineering company working on de-extinction of species such as the woolly mammoth, dire wolf, thylacine, dodo and moa. It has also developed a 3D-printed artificial egg system for avian embryo development.

CEO / Founder
Ben Lamm
Team Size
51-200
Stage
Growth Stage
Total Funding
$555M
Latest Round
Series C
Key Investors
TWG Global; Thomas Tull; Draper Associates; Breyer Capital; Winklevoss Capital Management; Animoca Brands; Bold Capital; Jazz Ventures

Technology & Products

Key Products

De-extinction programs (woolly mammoth, dire wolf, thylacine, dodo, moa, bluebuck); artificial egg system with a rigid hexagonal support cup and a semi-permeable silicone gas-exchange membrane (prototypes printed on Formlabs Form 4 in BioMed Black resin, final iterations in titanium); avian primordial germ cell culture technology; Colossal Foundation; spinouts Form Bio and Astromech.

Technological Advantage

Large capital base (over $555M raised) and a team of about 170 scientists plus advisors; co-founded by Harvard geneticist George Church; artificial egg platform uses AM for geometric control and scales from hummingbird-sized to moa-sized eggs.

Differentiation

Value Proposition

Develops genetic engineering, reproductive and enabling technologies, including artificial incubation hardware, to revive extinct species and support conservation of endangered ones.

How They Differentiate

Venture-backed, for-profit model with a large capital base and spinout monetization strategy, in contrast to non-profit and academic efforts; develops enabling hardware such as 3D-printed artificial eggs in-house.

Market & Competition

Target Customers

Conservation organizations, governments and research institutions. Commercial value is captured through technology spinouts such as Form Bio (software) and Astromech (AI).

Industry Verticals

Biotechnology; conservation biology; developmental biology; avian/poultry science; genomics

Competitors

Revive & Restore (non-profit genetic rescue); University of Melbourne TIGRR Lab (academic thylacine de-extinction)

Growth & Milestones

Growth Metrics

About 170 employees (2025). Valuation rose from over $1B (2023) to $10.2B (January 2025) and $10.32B (September 2025).

Major Milestones

2021-09: Launched with $15M seed; 2022-03: $60M Series A; 2022-09: Spun out Form Bio; 2023-01: $150M Series B; 2024-10: Launched Colossal Foundation; 2025-01: $200M Series C; 2025-09: $120M Series C extension and pigeon PGC breakthrough; 2025-11: Acquired Viagen; 2026-05: Hatched 26 chickens from 3D-printed artificial eggs.

Recent coverage of Colossal Biosciences

AM patents

AM-relevant patents linked to this company.

Patents
1
Granted
0
Families
1

Leading domains: process (1)

Filings by year: 2022: 1

  1. THREE-DIMENSIONAL CO-CULTURE SYSTEM FOR EMBRYOS CULTURED IN VITRO AND USES THEREOF2024081614 · WO

Funding rounds

  • Series C$120M2025-09Source
  • Series C$200M2025-01Lead: TWG Global · Source
  • Series B$150M2023-01Source
  • Series A$60M2022-03Lead: Thomas Tull · Source
  • Seed$15M2021-09Lead: Thomas Tull · Source