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SI-BONE

ApplicationSanta Clara, CA, USAFounded 2008· One of 690 Application companies tracked by AMPulse

Develops and commercializes minimally invasive sacroiliac (SI) joint fusion implants, including the 3D-printed iFuse 3D implant, to address SI joint dysfunction and related sacropelvic disorders.

CEO / Founder
Laura A. Francis
Team Size
201-500
Stage
Public
Total Funding
$81.1M
Latest Round
IPO
Key Investors
Skyline Ventures

Technology & Products

Key Products

iFuse Implant System; iFuse 3D Implant; iFuse TORQ Implant System

Technological Advantage

SI-BONE's iFuse 3D implant leverages additive manufacturing to create a porous surface that enhances bone integration, a key differentiator in orthopedic implants. The company holds 34 U.S. patents (as of June 2018) protecting its implant designs and surgical methods. The technology is protected by patents and regulatory clearances, making it difficult for competitors to replicate directly.

Differentiation

Value Proposition

Provides a minimally invasive surgical solution for SI joint dysfunction, reducing recovery time and improving patient outcomes compared to traditional fusion surgery, with the iFuse 3D implant's porous structure designed to enhance bone integration.

How They Differentiate

SI-BONE is the pioneer and market leader in minimally invasive SI joint fusion, with a dedicated focus on this niche. Its iFuse 3D implant is one of the first 3D-printed titanium implants cleared by the FDA for this indication, offering a unique porous structure for bone integration compared to competitors' solid implants.

Market & Competition

Target Customers

Hospitals, ambulatory surgery centers, and surgeons treating SI joint dysfunction

Industry Verticals

Medical Devices; Orthopedics

Competitors

Globus Medical; Medtronic; SIGNUS Medizintechnik

Growth & Milestones

Growth Metrics

Worldwide revenue of $56.3 million in Q4 2025; 2026 revenue guidance of $228.5 million; Q2 2026 revenue of $56M with 15% growth; U.S. procedure volume growth of 22%.

Major Milestones

2018: IPO on NASDAQ; 2019: Partnership with PrinterPrezz for 3D-printed implants; 2025: Record Q4 financial results

Notable Customers

Hospitals; Ambulatory surgery centers; Surgeons